Novel inflammatory markers and prognostic importance of platinum-sensitive ovarian carcinoma relapse

Introduction/Objective. Ovarian carcinomas are the deadliest gynecological tumors. Despite advances in treatment options, survival rates still not at desired level. Since clinical signs typical early-stage disease, 2/3rd of patients diagnosed late. Carbohydrate Antigen 125 (CA125) does have sufficient sensitivity and specificity disease early post-relapse progression. There is a need for simple cost-effective marker that correlates with CA125. For this purpose, we aimed to evaluate potential systemic inflammatory markers? as diagnostic aids. Methods. Patients platinum-sensitive recurrent ovarian were preferred because options more diverse than resistant group. Using retrospective data collection, 105 carcinoma, admitted last four years included study. Complete blood count was recorded based on recurrence progression periods. Results. When immune index (SII) values evaluated combination CA125 terms during control visits after treatment, detection proportions increased 97.5%, which 82.9% when only used. On other hand, false positivity, 18.5% alone, decreased 2.5% combined SII. Furthermore, neutrophil lymphocyte ratio, WBC, showed correlations high values. Conclusion. The SII value could be used together it easy use, accessible, has low cost practice, well increase accuracy rate make precise corrections positivity rate.